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Karma can refer to several things within the Megami Tensei franchise:
- Kamakura Gongoro: A Fool Arcana Persona who was renamed "Karma" for the English release of Revelations: Persona.
- Karma (race): An race of enemies in Megami Ibunroku Persona which represent the 7 deadly sins.
- Karma Temple: A location from Digital Devil Saga: Avatar Tuner. A huge tower which leads to Nirvana. It also functions as the administration in the Junkyard.
- Karma Society: An organization in Digital Devil Saga: Avatar Tuner 2.
- Karma: A term from Digital Devil Saga: Avatar Tuner that refers to Experience points.